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Protein profiling and identification of modulators regulated by human papillomavirus 16 E7 oncogene in HaCaT keratinocytes by proteomics

โœ Scribed by Kyung-Ae Lee; Jeong-Woo Kang; Jung-Hyun Shim; Chang Won Kho; Sung Goo Park; Hee Gu Lee; Sang-Gi Paik; Jong-Seok Lim; Do-Young Yoon


Book ID
113959994
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
422 KB
Volume
99
Category
Article
ISSN
0090-8258

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Expression of the human papillomavirus (HPV) type 16 E6 and E7 gene products is a risk factor for human cervical carcinogenesis as well as skin and oral carcinogenesis. Expression of the HPV-16 E7 gene in mouse skin induces hyperplasia and enhances tumor promotion. Expression of dominant-negative c-