Protein processing and morphogenesis of Paramecium secretory granules
β Scribed by Gautier, M.-C.; Madeddu, L.; Loubresse, Garreau N.; Sperling, L.
- Book ID
- 122126565
- Publisher
- Portland Press
- Year
- 1995
- Tongue
- English
- Weight
- 178 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0248-4900
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We examined the possibility that rat atrial granules may contain a pro-ANF processing protease. Isolated atrial granules were lysed either by detergent, osmotic shock or sonication and incubated at 37 degrees C. Pro-ANF processing and/or degradation were followed by radioimmunoassays and Western blo
Regulated secretory proteins are stored within specialized vesicles known as secretory granules. It is not known how proteins are sorted into these organelles. Regulated proteins may possess targeting signals which interact with specific sorting receptors in the lumen of the trans-Golgi network (TGN