Protein polymorphism in sheep pedigree testing
β Scribed by Shiquan Wang; W.C. Foote
- Book ID
- 119498127
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 326 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0093-691X
No coin nor oath required. For personal study only.
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A statistical model that uses an iterative maximum likelihood estimation procedure is proposed for measuring and testing the association between polymorhphic genetic markers and quantitative traits in human pedigrees, after adjusting for covariates such as age and sex. The model allows the quantitat
## Abstract Female relatives of 41 Duchenne muscular dystrophy proband cases were studied with a panel of carrierβdetection tests. A total of 277 relatives were tested in order to determine which mothers had affected sons as a result of new mutation. In 39 of 41 pedigrees the data demonstrate that