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Protein phosphatases that regulate multifunctional Ca2+/calmodulin-dependent protein kinases: from biochemistry to pharmacology

✍ Scribed by Atsuhiko Ishida; Yasushi Shigeri; Takanobu Taniguchi; Isamu Kameshita


Book ID
113845526
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
505 KB
Volume
100
Category
Article
ISSN
0163-7258

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## Abstract Maintenance of Ξ²1 integrin‐mediated cell adhesion in quiescent human mammary epithelial (HME) cells requires protein phosphatase (PP) 2A for not only dephosphorylation of Ξ²1 integrin but also recruitment of IQGAP1 to Rac‐bound Ξ²1 integrin. However, how PP2A‐dependent regulatory machiner