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Protein phosphatase-2A modulates the serine and tyrosine phosphorylation of paxillin in Lewis lung carcinoma tumor variants

✍ Scribed by Jodi L. Jackson; M. Rita I. Young


Book ID
110348175
Publisher
Springer
Year
2002
Tongue
English
Weight
251 KB
Volume
19
Category
Article
ISSN
0262-0898

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## Abstract Compared to metastatic Lewis lung carcinoma (LLC) cells, nonmetastatic LLC cells have increased levels of activity of the protein phosphatase PP‐2A, which functions to limit their migration through transwell chambers. Inhibition of PP‐2A in nonmetastatic LLC stimulates their transmigrat