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Protein oxidation as a novel biomarker of bladder decompensation

✍ Scribed by Carmin M. Kalorin; Anita Mannikarottu; Paul Neumann; Robert Leggett; Joshua Weisbrot; Arnold Johnson; Barry A. Kogan; Robert M. Levin

Book ID: 109053948
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 178 KB
Volume: 102
Category: Article
ISSN: 1464-4096
DOI: 10.1111/j.1464-410x.2008.07567.x

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## Abstract Hemoglobin (Hb) adducts have long been used as dosimeters of exposure to xenobiotics and endogenously formed reactive metabolites. In this study, hemoglobin chains were separated from each other and their prosthetic heme groups and reacted with 4‐oxo‐2‐nonenal, a major breakdown product