## Abstract In a two step reaction, hexamethylbenzene consumes two molecules of singlet oxygen to form epidioxy hydroperoxide **3**. The first step involves a [4 + 2]βcycloaddition, which is followed by an eneβreaction. The structure of the intermediary endoperoxide **2** has been established spect
Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite
β Scribed by Tilman Grune; Lars-Oliver Klotz; Jeanette Gieche; Markus Rudeck; Helmut Sies
- Book ID
- 114274731
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 497 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0891-5849
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Simple acidification o f aqueous alkaline peroxynitrite quantitatively generates singlet ('Ag) molecular oxygen, detected and quantitated spectroscopically (1 270 nm). This observation provides a chemical basis for physiological cytotoxicity o f ONOO-generated i n the diffusioncontrolled reaction o
Uric acid, a cellular antioxidant, undergoes oxidation in the presence of one-electron oxidants as well as singlet oxygen. In the present work, the oxidation pathways and products formed from oxidation of the uric acid nucleoside are compared to the more commonly studied uric acid free base. A wider