Protein Misfolding, Aggregation and Conformational Disease: Protein Aggregation and Conformational Diseases

✍ Scribed by Vladimir N. Uversky, Anthony Fink

Publisher: Springer
Year: 2006
Tongue: English
Leaves: 450
Series: Protein Reviews
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This volume fills the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. It is devoted to the general questions of conformational disorders and includes discussion of involvement of such common factors as molecular chaperones, oxidative damage, proteasome, glycosoaminoglycans, serum amyloid protein P and several others in the development of different disorders. Some experimental techniques applicable for the visualization of protein deposition in vivo and in vitro are also present.

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