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Protein kinase Mζ is necessary and sufficient for LTP maintenance

✍ Scribed by Ling, Douglas S.F.; Benardo, Larry S.; Serrano, Peter A.; Blace, Nancy; Kelly, Matthew T.; Crary, John F.; Sacktor, Todd C.

Book ID
109941209
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
178 KB
Volume
5
Category
Article
ISSN
1097-6256

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## Abstract The persistent activity of protein kinase Mzeta (PKMζ), a brain‐specific, constitutively active protein kinase C isoform, maintains synaptic long‐term potentiation (LTP). Structural remodeling of the postsynaptic density is believed to contribute to the expression of LTP. We therefore e