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Protein kinase D (PKD): A novel target for diacylglycerol and phorbol esters

โœ Scribed by Enrique Rozengurt; James Sinnett-Smith; Johan Van Lint; Angela M. Valverde


Book ID
113194822
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
798 KB
Volume
333
Category
Article
ISSN
0027-5107

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โœ Robert D. Raffaniello; Jean-Piean Raufman ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 649 KB

## Abstract Stimulation of chief cells with carbachol or cholecystokinin (CCK) results in the production of inositol trisphosphate (IP~3~) and diacylglycerol (DAG). Although IP~3~ increases cell calcium concentration, thereby stimulating pepsinogen secretion, the role of DAG and its target, protein