Protein kinase CK2: a new view of an old molecular complex
β Scribed by Filhol, Odile; Martiel, Jean-Louis; Cochet, Claude
- Book ID
- 110032470
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 330 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1469-221X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Abnormally high constitutive activity of protein kinase CK2, levels of which are elevated in a variety of tumours, is suspected to underlie its pathogenic potential. The most widely employed CK2 inhibitor is 4,5,6,7βtetrabromobenzotriazole (TBB), which exhibits a comparable efficacy tow
Proceeding from the recent finding that the main components of the Ca++ signal pathway are located in small membrane protrusions on the surface of differentiated cells, called microvilli, a novel concept of cellular Ca++ signaling was developed. The main features of this concept can be summarized as