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Protein kinase C-α1b-adrenoceptor coimmunoprecipitation: effect of hormones and phorbol myristate acetate

✍ Scribed by Rocı́o Alcántara-Hernández; Dinorah Leyva-Illades; J.Adolfo Garcı́a-Sáinz


Book ID
114013909
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
337 KB
Volume
419
Category
Article
ISSN
0014-2999

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The effects of phorbol myristate acetate (PMA) and dexamethasone on protein kinase C (PK-C) activity and eicosanoid production were characterized in primary cultures of rat glial cells. PMA (1,000 ng/ml) treatment for 2 hr resulted in a maximal effect (a 4-fold increase in PGE, production). Longer e