𝔖 Bobbio Scriptorium
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Protein kinase C

✍ Scribed by Peter J. Parker; Axel Ullrich


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
316 KB
Volume
133
Category
Article
ISSN
0021-9541

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Protein kinase C
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I wanted to be a ballerina, but somehow, I ended up being a spectator and a student to the most intricate dance of all-that of an enzyme that performs center stage in the theater of cell signaling. Protein kinase C moves between cellular compart-ments, interacting with binding partners and second me

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Members of the protein kinase C family respond to second messengers and are involved in controlling a broad array of cellular functions. The overlapping specificity and promiscuity of these proteins has promoted the view that specific binding proteins constrain individual family members to create th

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## Abstract Oligodendrocytes (OL) play a significant physiological role in the central nervous system by creating the myelin sheath that allows for the efficient conduction of nerve impulses. Therefore, it is important to understand which signalling cascades define the proliferation, differentiatio

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## Abstract There are two known phosphorylation‐mediated inactivation mechanisms for TRPC3 channels. Protein kinase G (PKG) inactivates TRPC3 by direct phosphorylation on Thr‐11 and Ser‐263 of the TRPC3 proteins, and protein kinase C (PKC) inactivates TRPC3 by phosphorylation on Ser‐712. In the pre

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A series of analogues of balanol (I) in which the perhydroazepine ring and the p-hydroxybenzamide moiety have been combined into a simple acyclic linked unit are evaluated for their inhibitory properties. It is found that a three-carbon linkage is optimal. Substitution on the three-carbon chain is i