Protein Kinase C (Molecular Biology Intelligence Unit)

✍ Scribed by Lodewijk V. Dekker (Ed.)

• Publisher: Springer
• Year: 2004
• Tongue: English
• Leaves: 203
• Edition: 1
• Category: Library

✦ Synopsis

Protein Kinase C is a pivotal component of the mechanism that allows a cell to respond to its changing environment. In this book, the most significant advances in recent basic research on Protein Kinase C are explained by active researchers in the field. The first seven chapters provide a comprehensive account of the fundamental structural and biochemical properties of Protein Kinase C. The remaining chapters contain overviews of the function of Protein Kinase C, both in lower organisms and in mammalian cells, the latter with a focus on immune cells and nerve cells. This book is the only recent publication devoted entirely to Protein Kinase C and forms a major point of reference for those active in the field. In addition it will appeal to those with a general interest in biochemistry, cell biology, immunology and neurobiology.

✦ Table of Contents

Cover Page......Page 1
Inside Cover......Page 2
Copyright......Page 3
Contents......Page 4
Editor, Contributors......Page 7
Preface......Page 9
CHAPTER 1 - Introduction......Page 10
CHAPTER 2 - Structure, Function and Membrane Interactions of C1 Domains......Page 17
CHAPTER 3 - Structural and Functional Specialization of C2 Domains in Protein Kinase C......Page 25
CHAPTER 4 - Regulation of Protein Kinase C by Membrane Interactions......Page 45
CHAPTER 5 - Protein Kinase C Regulation by Protein Interactions......Page 58
CHAPTER 6 - Regulation of Protein Kinase C by Phosphorylation......Page 72
CHAPTER 7 - Down-Regulation of Protein Kinase C......Page 85
CHAPTER 8 - Protein Kinase C in Yeast: The Cell Wall Integrity Pathway......Page 96
CHAPTER 9 - Specificity in Atypical Protein Kinase C Signaling: The NF-κB Paradigm......Page 109
CHAPTER 10 - Protein Kinase C: A Molecular Information Storage Device in Neurons......Page 123
CHAPTER 11 - Involvement of PKC in the Sensation of Pain......Page 143
CHAPTER 12 - The Protein Kinase C Gene Module: Cellular Functions in T Lymphocytes......Page 156
CHAPTER 13 - Protein Kinase C Isotype Function in Neutrophils......Page 174
Index......Page 200