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Protein Kinase C Mediates Short-and Long-term Effects on Receptor Tyrosine Kinases : Regulation of Tyrosine Phosphorylation and Degradation

✍ Scribed by KLAUS SEEDORF; MARK SHERMAN; AXEL ULLRICH


Book ID
119871908
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
218 KB
Volume
766
Category
Article
ISSN
0890-6564

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Intracellular signaling proteins are very often regulated by site-specific phosphorylation. For example, growth factor receptors in eukaryotic cells contain intrinsic tyrosine kinase activity and use inter- and intra-molecular interactions to recruit and orient potential protein substrates for phosp