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Protein Kinase C Is Not Involved in the Homologous Desensitization of Bombesin Responses in Small Cell Lung Cancer Cells

โœ Scribed by Andrea Frankel; Jean Viallet

Book ID
115601617
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
185 KB
Volume
209
Category
Article
ISSN
0014-4827

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๐Ÿ“œ SIMILAR VOLUMES

Homologous desensitization of bombesin-i
Homologous desensitization of bombesin-induced increases in intracellular Ca2+ in quiescent swiss 3T3 cells involves a protein kinase C-independent mechanism
โœ John H. Walsh; Mark Bouzyk; Enrique Rozengurt ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 856 KB

Addition of bombesin to Swiss 3T3 cells causes a rapid and transient increase in the intracellular concentration of Ca2+ ([Ca'+li), which is followed by desensitization to a subsequent addition of the peptide. The concentrations of bombesin used to study this acute cellular desensitization (0.1-0.5