Protein Glycosylation

✍ Scribed by Roslyn M. Bill M.A., D.Phil., M.R.S.C., C.Chem., Leigh Revers M.A., D.Phil., Iain B. H. Wilson B.Sc.(Hons), D.Phil., M.R.S.C., C.Chem. (auth.)

• Publisher: Springer US
• Year: 1998
• Tongue: English
• Leaves: 516
• Edition: 1
• Category: Library

✦ Synopsis

Protein Glycosylation provides clear, up-to-date, and integrated coverage of key topics in this field. Particular emphasis is placed on the biosynthetic pathways that result in a wide variety of identified protein-bound oligosaccharides. Protein Glycosylation begins with an overview of the chemical structures of mono- and oligosaccharides, to provide a scientific basis for the later chapters. The book includes discussions on the purification, function, and enzyme kinetics of selected glycosidases and glycotransferases, as well as a review of the roles of oligosaccharides in glycoprotein function and the in vivo role of glycoproteins themselves. Finally, the in vitro synthesis of glycoproteins is presented, together with future directions in glycobiology.
Protein Glycosylation serves as an excellent text for upper-level undergraduate and graduate students as well as a reference for those scientists whose training is not in glycobiology but who are moving into this field.

✦ Table of Contents

Front Matter....Pages i-xx
Sugars and Proteins: Getting It Together....Pages 1-48
Sugars And Proteins: Why They Get It Together....Pages 49-83
Sugars And Proteins: How They Get It Together....Pages 85-145
Core Issues: Building The Groundwork for N -Linked Sugars....Pages 147-212
Branching Out: Constructing The Antennae Of N -Linked Sugars....Pages 213-279
And What About O -Linked Sugars?....Pages 281-327
Adding The Finishing Touches: Terminal Elaborations....Pages 329-409
Expect The Unexpected: Unfamiliar Glycosylations....Pages 411-456
Complementing The Cell: Glycoform Synthesis In Vitro....Pages 457-491
Icing On The Cake: Summary And Future Directions....Pages 493-497
Back Matter....Pages 499-508

✦ Subjects

Biochemistry, general; Pharmacy; Oncology