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Protein folds from pair interactions: A blind test in fold recognition

✍ Scribed by Flöckner, Hannes; Domingues, Francisco S.; Sippl, Manfred J.

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
159 KB
Volume
29
Category
Article
ISSN
0887-3585

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✦ Synopsis

We submitted nine predictions to CASP2 using our fold recognition program ProFIT. Two of these structures were still unsolved by the end of the experiment, six had a recognizable fold, and one fold was new. Four predictions of the six recognizable folds were correct. Two models were excellent in terms of alignment quality (T0031, T0004): in one the alignment was partially correct (T0014), and one fold was correctly identified (T0038). We discuss improvements of the program and analyze the prediction results. Proteins, Suppl.

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