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Protein folding: Prolyl isomerases join the fold

✍ Scribed by Franz X. Schmid


Book ID
114320749
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
239 KB
Volume
5
Category
Article
ISSN
0960-9822

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Prolyl isomerases catalyze antibody fold
✍ Hauke Lilie; Johannes Buchner; Kurt Lang; Rainer Rudolph πŸ“‚ Article πŸ“… 1993 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 736 KB

## Abstract Some slow‐folding phases in the in vitro refolding of proteins originate from the isomerization of prolyl‐peptide bonds, which can be accelerated by a class of enzymes called prolyl isomerases (PPIs). We used the in vitro folding of an antibody Fab fragment as a model system to study th