Protein Folding: Folding helpers and unhelpful folders
β Scribed by Robert B. Freedman
- Book ID
- 114317405
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 381 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0960-9822
No coin nor oath required. For personal study only.
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An important idea that emerges from the energy landscape theory of protein folding is that subtle global features of the protein landscape can profoundly affect the apparent mechanism of folding. The relationship between various characteristic temperatures in the phase diagrams and landmarks in the
A universal strategy for obtaining maximal protein expression or refolding remains elusive; however, headway has been made toward understanding these processes in vivo. The observation of reversible protein aggregation, asymmetry in protein--chaperone complexes, redox effects on disulfide formation,