Protein folding: Chaperone embrace
โ Scribed by Cesari, Francesca
- Book ID
- 109958995
- Publisher
- Nature Publishing Group
- Year
- 2008
- Tongue
- English
- Weight
- 177 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1471-0072
- DOI
- 10.1038/nrm2441
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A universal strategy for obtaining maximal protein expression or refolding remains elusive; however, headway has been made toward understanding these processes in vivo. The observation of reversible protein aggregation, asymmetry in protein--chaperone complexes, redox effects on disulfide formation,
## Abstract The discovery of โmolecular chaperonesโ has dramatically changed our concept of cellular protein folding. Rather than folding spontaneously, most newly synthesized polypeptide chains seem to acquire their native conformation in a reaction mediated by these versatile helper proteins. Und