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Protein Folding as Biased Conformational Diffusion

✍ Scribed by Sullivan, David C.; Kuntz, Irwin D.

Book ID: 126246535
Publisher: American Chemical Society
Year: 2002
Tongue: English
Weight: 119 KB
Volume: 106
Category: Article
ISSN: 0022-3654
DOI: 10.1021/jp012911g

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## Abstract An important, but often neglected, contribution to the thermodynamics of protein folding is the loss of entropy that results from restricting the number of accessible side‐chain conformers in the native structure. Conformational entropy changes can be found by comparing the number of ac