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Protein folding and interactions revealed by mass spectrometry

✍ Scribed by Alexander M Last; Carol V Robinson

Book ID
104415114
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
213 KB
Volume
3
Category
Article
ISSN
1367-5931

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✦ Synopsis

Mass spectrometry is capable of examining very large, dynamic proteins and this ability, coupled with its relatively high throughput and low sample requirements, is reflected by its increasing importance for the characterisation of protein structure. Recent developments in mass spectrometry, in particular the refinement of the electrospray process and its coupling with time-of-flight mass analysis, mean that it is poised to contribute not only as a complementary tool but also with a defined role in many areas of chemical biology.

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