Protein Export and Membrane Biogenesis

✍ Scribed by Alan M. Tartakoff and Ross E. Dalbey (Eds.)

Publisher: Elsevier Science
Year: 1995
Tongue: English
Leaves: 297
Series: Advances in Cellular and Molecular Biology of Membranes and Organelles 4
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

The incentive for putting together Volume 4 of this series was to review the wealth of new information that has become available in prokaryotic organisms in protein export and membrane biogenesis. Just in the last several years, protein translocation has now been efficiently reconstituted using defined components and the mechanism by which proteins are moved across membrane bilayers is now being examined at a higher resolution. In addition, because of a new technical breakthrough using osmolytes, it is now possible to reconstitute a number of channel proteins, ATPase, receptors, and transporters. In many cases, it is possible to successfully predict the membrane topology of these types of proteins using both "hydrophobicity analysis" and the "positive inside" rule. In this volume, two chapters focus on protein translocation across membranes ( Biochemical Analyses of Components Comprising the Protein Translocation Machinery of E. Coli; Protein Translocation Genetics ), while several others on how proteins assemble into the ineer membrane of E. Coli ( Membrane Protein Assembly; Membrane Insertion of Small Proteins: Evolutionary and Functional Aspects; Pigment-Protein Complex Assembly in Rhodobacter sphaeroides and Rhodobacter Capsulatus ). Other sections review recent progress on transporters ( Identification and Reconstitution of Anion Exchange Mechanisms in Bacteria; Helic Packing in the C-Terminal Half of Lactose Permease ) and signal transduction ( Mechanism of Transmembrane Signaling in Osmoregulation ) as well as the assembly of prints into the outer membrane ( Export and Assembly of Outer Membrane Proteins in E. coli ). Although the emphasis of the book is on proteins, the role of phospholipids in controlling various cell surface processes is reviewed ( Role of Phospholipids in coli Cell Function ). I should point out the reason for the rapid progress in bacteria research is because of the possibility to apply biochemistry and genetics in this organism.

✦ Table of Contents

Content:
List of contributors
Pages vii-ix

Introduction to the series Original Research Article
Page xi
Alan M. Tartakoff

Preface
Pages xiii-xiv
Ross E. Dalbey

Membrane protein assembly Review Article
Pages 1-16
Paul Whitley, Gunnar von Heijne

Membrane insertion of small proteins: Evolutionary and functional aspects Review Article
Pages 17-33
Dorothee Kiefer, Andreas Kuhn

Protein translocation genetics Review Article
Pages 35-60
Koreaki Ito

Biochemical analyses of components comprising the protein translocation machinery of Escherichia coli Review Article
Pages 61-84
Shin-ichi Matsuyama, Shoji Mizushima

Pigment-protein complex assembly in rhodobacter sphaeroides and rhodobacter capsulatus Review Article
Pages 85-104
Amy R. Varga, Samuel Kaplan

Identification and reconstitution of anion exchange mechanisms in bacteria Review Article
Pages 105-128
Atul Varadhachary, Peter C. Maloney

Helix packing in the C-terminal half of lactose permease Review Article
Pages 129-144
H. Ronald Kaback, Kirsten Jung, Heinrich Jung, Jianhua Wu, Gilbert G. Privé, Kevin Zen

Export and assembly of outer membrane proteins in E. coli Review Article
Pages 145-173
Jan Tommassen, Hans de Cock

Structure-function relationships in the membrane channel porin Review Article
Pages 175-187
Georg E. Schulz

Role of phospholipids in Escherichia coli cell function Review Article
Pages 189-217
William Dowhan

Mechanism of transmembrane signaling in osmoregulation Review Article
Pages 219-262
Arfaan A. Rampersaud

Index
Pages 263-276

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