Protein evolution: Tracing the evolution of structure and function
β Scribed by Mullard, Asher
- Book ID
- 109958843
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 91 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1471-0072
- DOI
- 10.1038/nrm2263
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
How did enzyme catalysts evolve? First, a single catalytic group of rudimentary effectiveness could have been incorporated into a single short peptide. In the second stage, several peptides would bind together, providing a multichain assembly with improved catalytic effectiveness. These peptides wou
## Abstract Betaβcatenin functions as a cytoskeletal linker protein in cadherinβmediated adhesion and as a signal mediator in __wnt__βsignal transduction pathways. We use a novel integrative approach, combining evolutionary, genomic, and threeβdimensional structural data to analyze and trace the st