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Protein Design Using Unnatural Amino Acids

✍ Scribed by Bilgiçer, Basar; Kumar, Krishna


Book ID
126520685
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
578 KB
Volume
80
Category
Article
ISSN
0021-9584

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Here we describe the results of studies designed to explore the scope and limitations of expressed protein ligation (EPL), a protein semisynthesis approach that allows unnatural amino acids to be site specifically introduced into large proteins. Using Src homology 3 domains from the proteins c-Abl a