✦ LIBER ✦

Protein conformational dynamics dictate the binding affinity for a ligand

✍ Scribed by Seo, Moon-Hyeong; Park, Jeongbin; Kim, Eunkyung; Hohng, Sungchul; Kim, Hak-Sung

Book ID: 121754952
Publisher: Nature Publishing Group
Year: 2014
Tongue: English
Weight: 904 KB
Volume: 5
Category: Article
ISSN: 2041-1723
DOI: 10.1038/ncomms4724

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Accounting for Ligand Conformational Res

Accounting for Ligand Conformational Restriction in Calculations of Protein-Ligand Binding Affinities

✍ Gao, Cen; Park, Min-Sun; Stern, Harry A. 📂 Article 📅 2010 🏛 Biophysical Society 🌐 English ⚖ 387 KB

Dynamic ligand binding dictates partial

Dynamic ligand binding dictates partial agonism at a G protein–coupled receptor

✍ Bock, Andreas; Chirinda, Brian; Krebs, Fabian; Messerer, Regina; Bätz, Julia; Mu 📂 Article 📅 2013 🏛 Nature Publishing Group 🌐 English ⚖ 513 KB

A Recombinant Glutamine-Binding Protein

A Recombinant Glutamine-Binding Protein from Escherichia coli: Effect of Ligand-Binding on Protein Conformational Dynamics

✍ Petr Herman; Jaroslav Vecer; Viviana Scognamiglio; Maria Staiano; Mose' Rossi; S 📂 Article 📅 2004 🏛 American Institute of Chemical Engineers 🌐 English ⚖ 293 KB

A New Concept for Multidimensional Selec

A New Concept for Multidimensional Selection of Ligand Conformations (MultiSelect) and Multidimensional Scoring (MultiScore) of Protein−Ligand Binding Affinities

✍ Terp, Gitte Elgaard; Johansen, Bent Nagstrup; Christensen, Inge Thøger; Jørgense 📂 Article 📅 2001 🏛 American Chemical Society 🌐 English ⚖ 137 KB

Affinity labeling of a mouse IgB2a myelo

Affinity labeling of a mouse IgB2a myeloma protein with binding affinity for nitrophenyl ligands

✍ Martin, Nancy; Warner, Noel L.; Roeder, Phoebe E.; Singer, S. J. 📂 Article 📅 1972 🏛 American Chemical Society 🌐 English ⚖ 822 KB

A novel method for protein-ligand bindin

A novel method for protein-ligand binding affinity prediction and the related descriptors exploration

✍ Shuyan Li; Lili Xi; Chengqi Wang; Jiazhong Li; Beilei Lei; Huanxiang Liu; Xiaoju 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 365 KB

## Abstract In this study, a novel method was developed to predict the binding affinity of protein‐ligand based on a comprehensive set of structurally diverse protein‐ligand complexes (PLCs). The 1300 PLCs with binding affinity (493 complexes with __K__~d~ and 807 complexes with __K__~i~) from the