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Protein Classification Based on Physicochemical Descriptors

✍ Scribed by Meyer, Tim; Hensen, Ulf; Rex, Rene; Grubmueller, Helmut


Book ID
122206829
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
52 KB
Volume
98
Category
Article
ISSN
0006-3495

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## Abstract Within the last decades, the detailed knowledge on the impact of membrane bound drug efflux transporters of the ATP binding cassette (ABC) protein family on the pharmacological profile of drugs has enormously increased. Especially, ABCB1 (P‐glycoprotein, P‐gp, MDR1) has attracted partic