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Protein biosynthesis after lens rotation: An immunoelectrophoretic analysis in the chick embryo

✍ Scribed by Génis-Gálvez, J. M. ;Castro, J. M.


Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
404 KB
Volume
177
Category
Article
ISSN
0022-104X

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✦ Synopsis


An experimental, immunological analysis was performed to observe whether induced fiber cell formation i n the chick lens can be correlated with the biosynthesis of a specific crystallin. As a result of lens inversion, epithelial cells abruptly elongate. In these elongated cells crystallin determinants were uniquely predominant. These results seem to indicate that the quiescent genome of lens epithelial cells can be activated with a n appropriate artificial stimulus. Moreover, biosynthesis of delta crystallin, at least initially, seems to be strongly correlated with morphological features of lens fiber differentiation.