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Protein binding of glycopeptide antibiotics with diverse physical-chemical properties in mouse, rat, and human serum

โœ Scribed by Robert W. Wittendorf; James E. Swagzdis; Ralph Gifford; Bruce A. Mico


Book ID
112473850
Publisher
Springer
Year
1987
Tongue
English
Weight
533 KB
Volume
15
Category
Article
ISSN
1573-8744

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The serum protein binding of phenytoin, salicylic acid, sulfisoxazole, and warfarin was determined in normal human adults, in patients with impaired renal function (kidney donor and recipient), and in adult male Sprague--Dawley rats. The free fraction values for salicylate and sulfisoxazole were sig