Protein arrays and microarrays

✍ Scribed by Heng Zhu; Michael Snyder

• Book ID: 104414498
• Publisher: Elsevier Science
• Year: 2001
• Tongue: English
• Weight: 182 KB
• Volume: 5
• Category: Article
• ISSN: 1367-5931
• DOI: 10.1016/s1367-5931(00)00170-8

✦ Synopsis

In the past, studies of protein activities have focused on studying a single protein at a time, which is often time-consuming and expensive. Recently, with the sequencing of entire genomes, large-scale proteome analysis has begun. Arrays of proteins have been used for the determination of subcellular localization, analysis of protein-protein interactions and biochemical analysis of protein function. New protein-microarray technologies have been introduced that enable the high-throughput analysis of protein activities. These have the potential to revolutionize the analysis of entire proteomes.