Protein and ribonucleic acid synthesis in articular cartilage of osteoarthritic dogs
β Scribed by Henry J. Mankin; Patrick G. Laing
- Publisher
- John Wiley and Sons
- Year
- 1967
- Tongue
- English
- Weight
- 546 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0004-3591
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π SIMILAR VOLUMES
We have recently described a 550,000-dalton nomollagenous cartilage matrix glycoprotein (CMGP), with subunits of 130,000, which is present in hyaline cartilage and fibrocartilage. Biosynthetic studies indicated that CMGP was synthesized by short-term organ cultures of normal canine articular cartila
Proteases have been postulated to account for the progressive disappearance of matrix proteoglycans in osteoarthritic (OA) cartilage. The digestion of endogenous proteoglycans by neutral proteases in human OA cartilage homogenates has been measured and compared with that of normal age-matched contro
## Abstract ## Objective To observe redifferentiation of dedifferentiated chondrocytes after transplantation into the joint, and to evaluate the ability of dedifferentiated chondrocytes transduced with adenovirus containing bone morphogenetic protein 4 (BMPβ4) to redifferentiate in vitro and in vi