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Protein aggregate formation induced by lysosomal membrane permeability in lysosomal disease

✍ Scribed by Micsenyi, Matthew; Walkley, Steve

Book ID
122794056
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
63 KB
Volume
108
Category
Article
ISSN
1096-7192

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The protein composition of the integral lysosomal membrane and the membrane-associated compartment have been defined in part by proteomics approaches. While the role of its constituent hydrolases in a large array of human disorders has been well-documented, the manner in which membrane proteins are