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Protein adsorption from human plasma is reduced on phospholipid polymers

✍ Scribed by Ishihara, Kazuhiko ;Ziats, Nicholas P. ;Tierney, Brian P. ;Nakabayashi, Nobuo ;Anderson, James M.

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
746 KB
Volume
25
Category
Article
ISSN
0021-9304

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✦ Synopsis

Protein adsorption from human plasma was investigated on phospholipid polymers, poly (2-methacryloyloxyethyl phosphorylcholine (MPC)-co-n-butyl methacrylate (BMA) or glass by radioimmunoassay and immunogold labeling techniques. In the present studies the focus was to determine the composition and distribution of proteins at the surface of these materials after contact with human blood plasma. On all materials, protein adsorption was detected and included identification of albumin, IgG, fibrinogen, fibronectin, Hageman factor (factor XII), factor VIII/von Willebrand

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