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Protective effects of transgene expressed human PON3 against CCl4-induced subacute liver injury in mice

โœ Scribed by Wei Peng; Xiaoling Jiang; Lv Haiqin; Chi Zhang; Jie Zhu; Junfeng Zhang; Yuhui Zang; Junchuan Qin

Book ID
116314138
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
1011 KB
Volume
63
Category
Article
ISSN
0753-3322

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Transgene expression of human PON1 Q in mice protected the liver against CCl4-induced injury
โœ Chi Zhang; Wei Peng; Xiaoling Jiang; Bo Chen; Jie Zhu; Yuhui Zang; Junfeng Zhang ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 277 KB

## Background: Oxidative stress, often in association with decreased antioxidant defenses, plays a pathogenetic role in both initiation and progression of liver injuries, leading to almost all clinical and experimental conditions of chronic liver diseases. human paraoxonase 1 (hpon1) is a liver-syn