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Protective effects of TJ-48 on toxic side effects by CIS-diamminedichloroplatinum in mice

✍ Scribed by Kiyoshi Sugiyama; Masami Yokota; Harumi Ueda; Yoshimasa Ichio

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
74 KB
Volume
13
Category
Article
ISSN
0192-0561

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Primary colon tumors of different sizes and malignancy, chemically induced by methylazoxymethanol in outbred CF-1 mice, were used to investigate the antitumor effects of 5-Fluorouracil (5FU) and cis-diammine-dichloroplatinum (DDP), given weekly i.v. as single agents or in combination. When single-dr