Protective effects of the green tea polyphenol (−)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils
✍ Scribed by Seong-Ryong Lee; Seong-Il Suh; Sang-Pyo Kim
- Book ID
- 117470822
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 699 KB
- Volume
- 287
- Category
- Article
- ISSN
- 0304-3940
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## Abstract Previous studies have demonstrated that a green tea polyphenol, (−)‐epigallocatechine gallate (EGCG), has a potent free radical scavenging and antioxidant effect. Glutamate leads to excitotoxicity and oxidative stress, which are important pathophysiologic responses to cerebral ischemia
## Abstract Previous studies have demonstrated that (–)‐epigallocatechin gallate (EGCG), a green tea polyphenol, protects against ischemia and reperfusion‐induced injury in many organ systems. Here, we test the hypothesis that part of EGCG's neuroprotective effects may involve a modulation of matri