## Abstract Thalidomide, an inhibitor of tumor necrosis factorโฮฑ (TNFโฮฑ) production, has been indicated to be useful for many inflammatory and oncogenic diseases. In the present study, we examined whether thalidomide (50 mg/kg/day, p.o.) has a protective effect against NโmethylโDโaspartate (NMDA)โi
โฆ LIBER โฆ
Protective effects of selegiline and desmethylselegiline against N-methyl-d-aspartate-induced rat retinal damage
โ Scribed by Kazue Takahata; Hiroshi Katsuki; Yutaka Kobayashi; Shizuko Muraoka; Fumio Yoneda; Toshiaki Kume; Satoshi Kashii; Yoshihito Honda; Akinori Akaike
- Book ID
- 114015267
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 466 KB
- Volume
- 458
- Category
- Article
- ISSN
- 0014-2999
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## Abstract We investigated whether the neuroprotective effect of estrogen is mediated by the estrogen receptor (ER) and whether extracellular signalโregulated kinase (ERK) is involved in the protective effect of estrogen against __N__โmethylโDโaspartate (NMDA)โinduced retinal neurotoxicity. Retrog