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Protective effect of zinc on N-methyl-N-nitrosourea and testosterone-induced prostatic intraepithelial neoplasia in the dorsolateral prostate of Sprague Dawley rats

โœ Scribed by Banudevi, S.; Elumalai, P.; Sharmila, G.; Arunkumar, R.; Senthilkumar, K.; Arunakaran, J.


Book ID
121729772
Publisher
Royal Society of Medicine Press
Year
2011
Tongue
English
Weight
688 KB
Volume
236
Category
Article
ISSN
1535-3702

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Rat neoplasms induced by methylating carcinogens frequently contain ras genes activated by a single point mutation. Rat prostatic tumors induced by a combination of a single injection of N-methyl-N-nitrosourea (MNU) and long-term treatment with testosterone were examined for the presence of such act