Protective Effect of Sulforaphane on Human Vascular Endothelial Cells Against Lipopolysaccharide-Induced Inflammatory Damage
β Scribed by Yujuan Shan; Ruifang Zhao; Wei Geng; Na Lin; Xiaoxue Wang; Xiaoyan Du; Shuran Wang
- Book ID
- 107567531
- Publisher
- Humana Press Inc
- Year
- 2010
- Tongue
- English
- Weight
- 488 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1530-7905
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Up to date, the nature of the sepsisβinduced vascular leakage is understood only partially, which limits pharmacological approaches for its management. Here we studied the protective effect of cAMP using endotoxinβinduced hyperpermeability as a model for barrier dysfunction observed in
## Abstract Sulforaphane is known to be an indirect antioxidant that acts by inducing NFβE2βrelated factor 2 (Nrf2)βdependent phase II enzymes. In the present study, we investigated the effect of sulforaphane on the expression of heme oxygenaseβ1 (HOβ1) in human intestinal Int 407 cells. RTβPCR and