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Protective effect of pyrroloquinoline quinone against Aβ-induced neurotoxicity in human neuroblastoma SH-SY5Y cells

✍ Scribed by Jun-Jing Zhang; Rui-Fang Zhang; Xing-Kai Meng


Book ID
116771672
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
604 KB
Volume
464
Category
Article
ISSN
0304-3940

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## Abstract We investigated the effect of vanadate, a tyrosine phosphatase inhibitor, on cell death induced by peroxynitrite in human neuroblastoma SH‐SY5Y cells. Vanadate prevented cell death induced by 3‐morpholinosydnonimine (SIN‐1), a peroxynitrite donor; whereas SIN‐1‐induced cell death was no