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Protective effect of parathyroid hormone on hippocampal neurons in amyloid-beta 1-42 peptide-induced model of Alzheimer's disease in rats

✍ Scribed by Mnatsakanyan, Vazgen R.

Book ID: 122560294
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 46 KB
Volume: 5
Category: Article
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2009.04.544

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Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by loss of memory and cognition and by senile plaques and neurofibrillary tangles in brain. Amyloid-beta peptide, particularly the 42-amino-acid peptide (Abeta(1-42)), is a principal component of senile plaques and is