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Protective Effect Of Inhaled Salbutamol Powder In Children Assessed By Histamine Challenge

✍ Scribed by C. R. Pullan and A. J. Martin


Book ID
125721395
Publisher
BMJ Publishing Group
Year
1980
Tongue
English
Weight
510 KB
Volume
280
Category
Article
ISSN
0959-8138

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The onset of effect of the H1-antagonist
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The onset of effect of acrivastine, a new H1-antagonist, has been assessed using antagonism of histamine-induced bronchoconstriction in sensitive volunteers. Acrivastine administered 30, 45, 60 or 90 min before challenge produced a right-shift of the histamine dose-response curve of at least 8-fold