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Protective effect of green tea against benzo[a]pyrene-induced mutations in the liver of Big Blue® transgenic mice

✍ Scribed by Tao Jiang; Barry W. Glickman; Johan G. de Boer

Book ID
114070439
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
106 KB
Volume
480-481
Category
Article
ISSN
0027-5107

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✍ Thomas R. Skopek; Kristy L. Kort; Deborah R. Marino; Lakshmi V. Mittal; Diane R. 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 807 KB

Big Blue@ (BB) and generic B6C3F1 mice were given one to three i.p. injections of 50 mg/kg benzo[a]pyrene (B[a]P) in DMSO every other day to achieve cumulative doses of 50 to 150 mg/kg. Three weeks after treatment, the mutation frequency at the endogenous hprt gene and lac/ transgene was measured in