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Protective effect of fosfomycin on gentamicin-induced lipid peroxidation of rat renal tissue

✍ Scribed by Chie Yanagida; Kousei Ito; Izumi Komiya; Toshiharu Horie

Book ID
113517051
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
229 KB
Volume
148
Category
Article
ISSN
0009-2797

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The intraperitoneal administration of gentamicin (100 mg kg[-1] day[-1]) to rats is associated with an increased production of malondialdehyde (MDA), which is an end product of lipid peroxidation in the kidney. The level of glutathione (GSH) and the activity of three antioxidant systems--superoxide