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Protective action of lipid- and water-soluble antioxidants on the cytochrome P-450 system during lipid peroxidation in liver microsomes

✍ Scribed by E. A. Serbinova; M. B. Kadiiska; V. A. Tyurin; V. E. Kagan; Ts. S. Stoichev


Publisher
Springer US
Year
1989
Tongue
English
Weight
181 KB
Volume
107
Category
Article
ISSN
0007-4888

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A 5-month treatment of rats with ethanol (10% solution in drinking water) stimulated aniline p-hydroxylase and the microsomal ethanol oxidizing system (MEOS) by 140 and 70%, respectively, cytochrome P-450 by 22% and accompanied by lipid peroxidation by 40% in microsomes. It also caused smooth endopl