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Protection of peroxiredoxin II on oxidative stress-induced cardiomyocyte death and apoptosis

โœ Scribed by Wen Zhao; Guo-Chang Fan; Zhi-Guo Zhang; Arun Bandyopadhyay; Xiaoyang Zhou; Evangelia G. Kranias

Book ID
106067127
Publisher
Springer
Year
2008
Tongue
English
Weight
539 KB
Volume
104
Category
Article
ISSN
0300-8428

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## Abstract We evaluated the antioxidant role of peroxiredoxin 6 (Prdx6) in primary lung alveolar epithelial type II cells (AEC II) that were isolated from wild type (WT), Prdx6โˆ’/โˆ’, or Prdx6 transgenic (Tg) overexpressing mice and exposed to H~2~O~2~ at 50โ€“500 ยตM for 1โ€“24 h. Expression of Prdx6 in