## Abstract Merrifield solid phase peptide synthesis has been the principle research procedure used in the study of the chemistry and biological use of deamidation of asparaginyl and glutaminyl residues in peptides and proteins during the past 40 years. During the initial years of investigation, it
โฆ LIBER โฆ
Protection of Peptides of Biological Origin for Use as Intermediates in the Chemical Synthesis of Proteins
โ Scribed by OFFORD, R. E.
- Book ID
- 109665405
- Publisher
- Nature Publishing Group
- Year
- 1969
- Tongue
- English
- Weight
- 489 KB
- Volume
- 221
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/221037a0
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In this communication we introduce a promising masking agent --the vinyloxycarbonyl or VOC group --for the protection of amino functions in peptide chemistry. Amino acids are easily converted to their N-VOC derivatives (l\_) in dilute aqueous base using the known vinyl chloroformate' in dioxane as t
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