𝔖 Bobbio Scriptorium
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Protection of foreign DNA against host-controlled restriction in bacterial cells

✍ Scribed by Krüger, D. H. ;Chernin, L. S. ;Hansen, Sigrid ;Rosenthal, H. A. ;Goldfarb, D. M.

Publisher
Springer
Year
1978
Tongue
English
Weight
418 KB
Volume
159
Category
Article
ISSN
0026-8925

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✦ Synopsis

Foreign F'lac plasmid DNA which is introduced into potentially restricting E. coli recipient cells can be protected from restriction by preinfecting the recipient cells with UV-inactivated T3 or T7 bacteriophages which express the ocr gene function. The recipient cells survive and are able to replicate themselves as well as the newly acquired plasmid.

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## Abstract The resistance of two biomaterials, one synthetic and one biologic in origin, to deliberate bacterial infection was compared in a dog model of orthopedic soft tissue reconstruction. Twenty‐four adult female dogs were randomly divided into two equal groups and a 2.0‐cm‐round full‐thickne