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Protection by inhibitors of multidrug resistance against mitochondrial mutagenesis in Saccharomyces cerevisiae

✍ Scribed by Baguley, Bruce C.; Turner, Pamela M.; Ferguson, Lynnette R.


Book ID
123361173
Publisher
Elsevier Science
Year
1990
Weight
642 KB
Volume
26
Category
Article
ISSN
0277-5379

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Suppression of mitochondrially-determine
✍ Waxman, Michael F. ;Knight, Jeffrey A. ;Perlman, Philip S. πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 689 KB

Phenotypic "revertants" of a drug resistant strain of Saccharomyces cerevisiae were induced by mutgenesis with manganese. Several of these drug sensitive mutants have been shown to result from mutations in the nuclear genome that cause phenotypic modification (suppression) of the mitochondrially-det